{
  "creator": [
    "Shedden-Mora, Meike C.",
    "Pan, Yiqi",
    "Heisig, Sarah R.",
    "von Blanckenburg, Pia",
    "Rief, Winfried",
    "Witzel, Isabell",
    "Albert, Ute-Susann",
    "Nestoriuc, Yvonne"
  ],
  "date": [
    "2020-03-31"
  ],
  "description": [
    "Background: Medication side effects are strongly determined by non-pharmacological, nocebo mechanisms, particularly patients’ expectations. Optimizing expectations could minimize side effect burden. This study evaluated whether brief psychological expectation management training (EXPECT) optimizes medication-related expectations in women starting adjuvant endocrine therapy (AET) for breast cancer.Method: In a multisite randomized controlled design, 197 women were randomized to EXPECT, supportive therapy (SUPPORT), or treatment as usual (TAU). The three-session cognitive-behavioral EXPECT employs psychoeducation, guided imagery, and side effect management training. Outcomes were necessity-concern beliefs about AET, expected side effects, expected coping ability, treatment control expectations, and adherence intention.Results: Both interventions were well accepted and feasible. Patients’ necessity-concern beliefs were optimized in EXPECT compared to both TAU and SUPPORT, d = .41, p < .001; d = .40, p < .001. Expected coping ability and treatment control expectations were optimized compared to TAU, d = .35, p = .02; d = .42, p < 001, but not to SUPPORT. Adherence intention was optimized compared to SUPPORT, d = .29, p = .02, but not to TAU. Expected side effects did not change significantly.Conclusion: Expectation management effectively and partly specifically (compared to SUPPORT) modified medication-related expectations in women starting AET. Given the influence of expectations on long-term treatment outcome, psychological interventions like EXPECT might provide potential pathways to reduce side effect burden and improve quality of life during medication intake."
  ],
  "format": [
    "application/pdf",
    "text/html",
    "application/xml"
  ],
  "identifier": [
    "https://cpe.psychopen.eu/index.php/cpe/article/view/2695",
    "10.32872/cpe.v2i1.2695"
  ],
  "language": [
    "eng"
  ],
  "publisher": [
    "PsychOpen GOLD / Leibniz Institut for Psychology (ZPID)"
  ],
  "relation": [
    "https://cpe.psychopen.eu/index.php/cpe/article/view/2695/2695.pdf",
    "https://cpe.psychopen.eu/index.php/cpe/article/view/2695/2695.html",
    "https://cpe.psychopen.eu/index.php/cpe/article/view/2695/2695.xml"
  ],
  "rights": [
    "Copyright (c) 2020 Meike C. Shedden-Mora, Yiqi Pan, Sarah R. Heisig, Pia von Blanckenburg, Winfried Rief, Isabell Witzel, Ute-Susann Albert, Yvonne Nestoriuc",
    "https://creativecommons.org/licenses/by/4.0"
  ],
  "source": [
    "Clinical Psychology in Europe; Vol. 2 No. 1 (2020); 1-20",
    "2625-3410",
    "10.32872/cpe.v2i1"
  ],
  "subject": [
    "expectation management",
    "nocebo effect",
    "psychological intervention",
    "side effect",
    "adjuvant endocrine treatment",
    "breast cancer",
    "oncology"
  ],
  "title": [
    "Optimizing Expectations About Endocrine Treatment for Breast Cancer: Results of the Randomized Controlled PSY-BREAST Trial"
  ],
  "type": [
    "info:eu-repo/semantics/article",
    "info:eu-repo/semantics/publishedVersion"
  ]
}